Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67429
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
19597±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67429
Synonyms:
(1-methylbenzimidazol-2-yl)methyl-[4-[4-(p-tolyl)piperazino]phenyl]amine | MLS000702121 | N-[(1-methyl-1H-benzimidazol-2-yl)methyl]-N-{4-[4-(4-methylphenyl)-1-piperazinyl]phenyl}amine | N-[(1-methyl-2-benzimidazolyl)methyl]-4-[4-(4-methylphenyl)-1-piperazinyl]aniline | N-[(1-methylbenzimidazol-2-yl)methyl]-4-[4-(4-methylphenyl)piperazin-1-yl]aniline | SMR000230166 | cid_7309526
Type:
Small organic molecule
Emp. Form.:
C26H29N5
Mol. Mass.:
411.542
SMILES:
Cc1ccc(cc1)N1CCN(CC1)c1ccc(NCc2nc3ccccc3n2C)cc1
Structure:
Search PDB for entries with ligand similarity: