Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67440
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
>75412±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67440
Synonyms:
4-(3-bromo-5-ethoxy-4-hydroxy-phenyl)-1-cyclopentyl-4H-pyridine-3,5-dicarboxylic acid dimethyl ester | 4-(3-bromo-5-ethoxy-4-hydroxyphenyl)-1-cyclopentyl-4H-pyridine-3,5-dicarboxylic acid dimethyl ester | MLS000911026 | SMR000073919 | cid_1313404 | dimethyl 4-(3-bromanyl-5-ethoxy-4-oxidanyl-phenyl)-1-cyclopentyl-4H-pyridine-3,5-dicarboxylate | dimethyl 4-(3-bromo-5-ethoxy-4-hydroxyphenyl)-1-cyclopentyl-1,4-dihydro-3,5-pyridinedicarboxylate | dimethyl 4-(3-bromo-5-ethoxy-4-hydroxyphenyl)-1-cyclopentyl-4H-pyridine-3,5-dicarboxylate
Type:
Small organic molecule
Emp. Form.:
C22H26BrNO6
Mol. Mass.:
480.349
SMILES:
CCOc1cc(cc(Br)c1O)C1C(=CN(C=C1C(=O)OC)C1CCCC1)C(=O)OC |c:13,16|
Structure:
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