Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM52859
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
16969±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM52859
Synonyms:
(4Z)-2-ethyl-4-(2-thenylidene)-1,3-dihydrobenzo[b][1,6]naphthyridine-10-carboxylic acid | (4Z)-2-ethyl-4-(thiophen-2-ylmethylidene)-1,3-dihydrobenzo[b][1,6]naphthyridine-10-carboxylic acid | MLS001003079 | SMR000372730 | cid_7515944
Type:
Small organic molecule
Emp. Form.:
C20H18N2O2S
Mol. Mass.:
350.434
SMILES:
CCN1C\C(=C\c2cccs2)c2nc3ccccc3c(C(O)=O)c2C1
Structure:
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