Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67441
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
10098±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67441
Synonyms:
4-(3-methyl-1-pyridin-1-iumyl)-5-[[(4-nitrophenyl)hydrazinylidene]methyl]-2-thiazololate | 4-(3-methylpyridin-1-ium-1-yl)-5-[[(4-nitrophenyl)hydrazinylidene]methyl]-1,3-thiazol-2-olate | 4-(3-methylpyridin-1-ium-1-yl)-5-[[(4-nitrophenyl)hydrazono]methyl]thiazol-2-olate | MLS001030197 | SMR000427297 | cid_3833004
Type:
Small organic molecule
Emp. Form.:
C16H13N5O3S
Mol. Mass.:
355.371
SMILES:
Cc1ccc[n+](c1)-c1[n-]c(=O)sc1CN=Nc1ccc(cc1)[N+]([O-])=O |w:15.17|
Structure:
Search PDB for entries with ligand similarity: