Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM53371
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
7261±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM53371
Synonyms:
MLS001097825 | N-(6-amino-1-isobutyl-2,4-diketo-pyrimidin-5-yl)-N-butyl-5-nitro-2-furamide | N-[6-amino-1-(2-methylpropyl)-2,4-dioxo-5-pyrimidinyl]-N-butyl-5-nitro-2-furancarboxamide | N-[6-amino-1-(2-methylpropyl)-2,4-dioxopyrimidin-5-yl]-N-butyl-5-nitrofuran-2-carboxamide | N-[6-azanyl-1-(2-methylpropyl)-2,4-bis(oxidanylidene)pyrimidin-5-yl]-N-butyl-5-nitro-furan-2-carboxamide | SMR000716020 | cid_24686901
Type:
Small organic molecule
Emp. Form.:
C17H23N5O6
Mol. Mass.:
393.3944
SMILES:
CCCCN(C(=O)c1ccc(o1)[N+]([O-])=O)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
Structure:
Search PDB for entries with ligand similarity: