Target
Protein Rev
Ligand
BDBM67450
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
>75472±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67450
Synonyms:
(E)-2-cyano-3-[4-(dimethylamino)phenyl]-2-propenoic acid [1-(2-furanylmethylamino)-1-oxopropan-2-yl] ester | (E)-2-cyano-3-[4-(dimethylamino)phenyl]acrylic acid [2-(2-furfurylamino)-2-keto-1-methyl-ethyl] ester | MLS001160854 | SMR000710902 | [1-(furan-2-ylmethylamino)-1-oxidanylidene-propan-2-yl] (E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoate | [1-(furan-2-ylmethylamino)-1-oxopropan-2-yl] (E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoate | cid_24688061
Type:
Small organic molecule
Emp. Form.:
C20H21N3O4
Mol. Mass.:
367.3984
SMILES:
CC(OC(=O)C(=C\c1ccc(cc1)N(C)C)\C#N)C(=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: