Reaction Details Report a problem with these data
Target
Protein Rev
Ligand
BDBM67452
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction
IC50
16416±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction PubChem Bioassay (2010)[AID] 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM67452
Synonyms:
5-(4-acetylphenyl)-N-(6-methoxy-3-pyridinyl)-2-furancarboxamide | 5-(4-acetylphenyl)-N-(6-methoxy-3-pyridyl)-2-furamide | 5-(4-acetylphenyl)-N-(6-methoxypyridin-3-yl)furan-2-carboxamide | 5-(4-ethanoylphenyl)-N-(6-methoxypyridin-3-yl)furan-2-carboxamide | MLS002171546 | SMR001251840 | cid_2467799
Type:
Small organic molecule
Emp. Form.:
C19H16N2O4
Mol. Mass.:
336.3413
SMILES:
COc1ccc(NC(=O)c2ccc(o2)-c2ccc(cc2)C(C)=O)cn1
Structure:
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