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TargetNADPH oxidase 1
LigandBDBM71623
Substrate/Competitorn/a
Meas. Tech.Late stage results from the probe development effort to identify inhibitors of NOX1: HEK/293 IC50 Set 2
IC50 4000±n/a nM
Citation PubChem, PC Late stage results from the probe development effort to identify inhibitors of NOX1: HEK/293 IC50 Set 2 PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
NADPH oxidase 1
Name:NADPH oxidase 1
Synonyms:MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1
Type:PROTEIN
Mol. Mass.:64890.44
Organism:Homo sapiens (Human)
Description:ChEMBL_792877
Residue:564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCL
NFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHL
FNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVI
MTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHP
RKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKV
VMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGD
WTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYK
FQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSN
IVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSL
RKCCHRYSSLDPRKVQFYFNKENF
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BDBM71623
NameBDBM71623
Synonyms:3,5-bis(chloranyl)-N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]pyridin-4-amine | 3,5-dichloro-N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]-4-pyridinamine | 3,5-dichloro-N-[(E)-[4-(dimethylamino)phenyl]methylideneamino]pyridin-4-amine | SR-01000639434-1 | [4-[(E)-[(3,5-dichloro-4-pyridyl)hydrazono]methyl]phenyl]-dimethyl-amine | cid_9566216
TypeSmall organic molecule
Emp. Form.C14H14Cl2N4
Mol. Mass.309.194
SMILESCN(C)c1ccc(CN=Nc2c(Cl)cncc2Cl)cc1 |w:9.9|
Structure
n/a