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Target
Heat shock factor protein 1
Ligand
BDBM35489
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)
EC50
>260000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM35489
Synonyms:
1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2-yl)-urea | MLS000035450 | N-[(3,4-dichloro-5-keto-2H-furan-2-yl)carbamoyl]acetamide | N-[(3,4-dichloro-5-oxo-2H-furan-2-yl)carbamoyl]acetamide | N-[[(3,4-dichloro-5-oxo-2H-furan-2-yl)amino]-oxomethyl]acetamide | N-[[3,4-bis(chloranyl)-5-oxidanylidene-2H-furan-2-yl]carbamoyl]ethanamide | SMR000001295 | cid_654815
Type:
Small organic molecule
Emp. Form.:
C7H6Cl2N2O4
Mol. Mass.:
253.04
SMILES:
CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl |c:12|
Structure:
Search PDB for entries with ligand similarity: