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Target
Heat shock factor protein 1
Ligand
BDBM71763
Substrate
n/a
Meas. Tech.
Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)
EC50
>260000±n/a nM
Citation
 PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay (2010)[AID] 
Target
Name:
Heat shock factor protein 1
Synonyms:
HSF1_MOUSE | Hsf1 | Hsf1 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57208.68
Organism:
Mus musculus
Description:
P38532
Residue:
525
Sequence:
MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVTSVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHAQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPYSAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQEPPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPALPTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTMPDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTGSSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
  
Inhibitor
Name:
BDBM71763
Synonyms:
3-[(4-chlorophenyl)sulfonylamino]-3-(2-furyl)-N-sec-butyl-propionamide | MLS000047308 | N-(sec-butyl)-3-{[(4-chlorophenyl)sulfonyl]amino}-3-(2-furyl)propanamide | N-butan-2-yl-3-[(4-chlorophenyl)sulfonylamino]-3-(2-furanyl)propanamide | N-butan-2-yl-3-[(4-chlorophenyl)sulfonylamino]-3-(furan-2-yl)propanamide | SMR000033319 | cid_3238922
Type:
Small organic molecule
Emp. Form.:
C17H21ClN2O4S
Mol. Mass.:
384.878
SMILES:
CCC(C)NC(=O)CC(NS(=O)(=O)c1ccc(Cl)cc1)c1ccco1
Structure:
Search PDB for entries with ligand similarity: