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Target
NADPH oxidase 1
Ligand
BDBM67509
Substrate
n/a
Meas. Tech.
Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Xanthine Oxidase Set 2
IC50
>50000±n/a nM
Citation
 PubChem, PC Late stage results from the probe development effort to identify inhibitors of (NADPH oxidase 1) NOX1: Xanthine Oxidase Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
NADPH oxidase 1
Synonyms:
MOX-1 | MOX1 | Mitogenic oxidase 1 | NADH/NADPH mitogenic oxidase subunit P65-MOX | NOH-1 | NOH1 | NOX-1 | NOX1 | NOX1_HUMAN
Type:
PROTEIN
Mol. Mass.:
64890.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792877
Residue:
564
Sequence:
MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF
  
Inhibitor
Name:
BDBM67509
Synonyms:
2,6-dibromo-4-[[(3,5-dichloro-4-pyridinyl)hydrazo]methylidene]-1-cyclohexa-2,5-dienone | 2,6-dibromo-4-[[2-(3,5-dichloropyridin-4-yl)hydrazinyl]methylidene]cyclohexa-2,5-dien-1-one | 2,6-dibromo-4-[[N'-(3,5-dichloro-4-pyridyl)hydrazino]methylene]cyclohexa-2,5-dien-1-one | 4-[[2-[3,5-bis(chloranyl)pyridin-4-yl]hydrazinyl]methylidene]-2,6-bis(bromanyl)cyclohexa-2,5-dien-1-one | SR-03000000731-1 | cid_5703786
Type:
Small organic molecule
Emp. Form.:
C12H7Br2Cl2N3O
Mol. Mass.:
439.917
SMILES:
Oc1c(Br)cc(CN=Nc2c(Cl)cncc2Cl)cc1Br |w:8.8|
Structure:
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