Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4H
Ligand
BDBM73160
Substrate
n/a
Meas. Tech.
SAR analysis for the identification of translation initiation inhibitors (eIF4H)
IC50
16100±n/a nM
Citation
 PubChem, PC SAR analysis for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay (2010)[AID] 
Target
Name:
Eukaryotic translation initiation factor 4H
Synonyms:
EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27385.24
Organism:
Homo sapiens (Human)
Description:
Q15056
Residue:
248
Sequence:
MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVQKEQE
  
Inhibitor
Name:
BDBM73160
Synonyms:
2-mesyl-N-(5-quinolyl)benzamide | 2-methylsulfonyl-N-(5-quinolinyl)benzamide | 2-methylsulfonyl-N-quinolin-5-yl-benzamide | 2-methylsulfonyl-N-quinolin-5-ylbenzamide | MLS-0356470.0001 | cid_2474595
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3S
Mol. Mass.:
326.37
SMILES:
CS(=O)(=O)c1ccccc1C(=O)Nc1cccc2ncccc12
Structure:
Search PDB for entries with ligand similarity: