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Target
G protein-activated inward rectifier potassium channel 1
Ligand
BDBM10759
Substrate
n/a
Meas. Tech.
Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response Testing
EC50
0.06142±n/a nM
Citation
 PubChem, PC Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response Testing PubChem Bioassay (2010)[AID] 
Target
Name:
G protein-activated inward rectifier potassium channel 1
Synonyms:
Girk1 | KCNJ3_RAT | Kcnj3 | Kga
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56581.73
Organism:
Rattus norvegicus
Description:
gi_13928834
Residue:
501
Sequence:
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEVVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDISTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGGPTRMEGNLPAKLRKMNSDRFT
  
Inhibitor
Name:
BDBM10759
Synonyms:
2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acetoxyethyl(trimethyl)ammonium;perchlorate | CHEMBL667 | US10667515, Compound ACh | [2-(acetyloxy)ethyl]trimethylazanium | acetylcholine | acetylcholine chloride | cid_6060
Type:
Small Organic Molecule
Emp. Form.:
C7H16NO2
Mol. Mass.:
146.2069
SMILES:
CC(=O)OCC[N+](C)(C)C
Structure:
Search PDB for entries with ligand similarity: