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Target
G protein-activated inward rectifier potassium channel 1
Ligand
BDBM42613
Substrate
n/a
Meas. Tech.
Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response with Rauwolscine
EC50
3152±n/a nM
Citation
 PubChem, PC Measurement of GPCR-mediated thallium flux through GIRK channels: Dose-Response with Rauwolscine PubChem Bioassay (2010)[AID] 
Target
Name:
G protein-activated inward rectifier potassium channel 1
Synonyms:
Girk1 | KCNJ3_RAT | Kcnj3 | Kga
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56581.73
Organism:
Rattus norvegicus
Description:
gi_13928834
Residue:
501
Sequence:
MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEVVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDISTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGGPTRMEGNLPAKLRKMNSDRFT
  
Inhibitor
Name:
BDBM42613
Synonyms:
3-allyl-2-thioxo-1H-quinazolin-4-one | 3-prop-2-enyl-2-sulfanylidene-1H-quinazolin-4-one | MLS000071463 | SMR000059240 | cid_657947
Type:
Small organic molecule
Emp. Form.:
C11H10N2OS
Mol. Mass.:
218.275
SMILES:
C=CCn1c(=S)[nH]c2ccccc2c1=O
Structure:
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