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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74444
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74444
Synonyms:
4-Isopropyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid [(benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-methyl ester | 4-isopropylfuro[3,2-b]pyrrole-5-carboxylic acid [2-keto-2-(piperonylamino)ethyl] ester | 4-propan-2-yl-5-furo[3,2-b]pyrrolecarboxylic acid [2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl] ester | MLS000035170 | SMR000008063 | [2-(1,3-benzodioxol-5-ylmethylamino)-2-oxidanylidene-ethyl] 4-propan-2-ylfuro[3,2-b]pyrrole-5-carboxylate | [2-(1,3-benzodioxol-5-ylmethylamino)-2-oxoethyl] 4-propan-2-ylfuro[3,2-b]pyrrole-5-carboxylate | cid_648085
Type:
Small organic molecule
Emp. Form.:
C20H20N2O6
Mol. Mass.:
384.3826
SMILES:
CC(C)n1c(cc2occc12)C(=O)OCC(=O)NCc1ccc2OCOc2c1
Structure:
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