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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74458
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74458
Synonyms:
1-(2,6-dimethyl-4-morpholinyl)-2-(4-methoxyphenoxy)-1-propanone | 1-(2,6-dimethylmorpholin-4-yl)-2-(4-methoxyphenoxy)propan-1-one | 1-(2,6-dimethylmorpholino)-2-(4-methoxyphenoxy)propan-1-one | 4-[2-(4-methoxyphenoxy)propanoyl]-2,6-dimethylmorpholine | MLS000066438 | SMR000081406 | cid_2974424
Type:
Small organic molecule
Emp. Form.:
C16H23NO4
Mol. Mass.:
293.3581
SMILES:
COc1ccc(OC(C)C(=O)N2CC(C)OC(C)C2)cc1
Structure:
Search PDB for entries with ligand similarity: