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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74480
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74480
Synonyms:
3-bromanyl-N'-(2-oxidanylidene-2-piperidin-1-yl-ethanoyl)benzohydrazide | 3-bromo-N'-[oxo(1-piperidinyl)acetyl]benzohydrazide | 3-bromo-N'-(2-keto-2-piperidino-acetyl)benzohydrazide | 3-bromo-N'-(2-oxo-2-piperidin-1-ylacetyl)benzohydrazide | 3-bromo-N'-[1,2-dioxo-2-(1-piperidinyl)ethyl]benzohydrazide | MLS000702262 | SMR000226176 | cid_7767931
Type:
Small organic molecule
Emp. Form.:
C14H16BrN3O3
Mol. Mass.:
354.199
SMILES:
Brc1cccc(c1)C(=O)NNC(=O)C(=O)N1CCCCC1
Structure:
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