Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM74483
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM74483
Synonyms:
MLS000702197 | N-[2-(carbethoxycarbamoyl)-3-(p-toluidino)acryloyl]carbamic acid ethyl ester | N-[2-[(ethoxycarbonylamino)-oxomethyl]-3-(4-methylanilino)-1-oxoprop-2-enyl]carbamic acid ethyl ester | SMR000226743 | cid_1815359 | ethyl 2-{[(ethoxycarbonyl)amino]carbonyl}-3-(4-toluidino)acryloylcarbamate | ethyl N-[2-(ethoxycarbonylcarbamoyl)-3-(4-methylanilino)prop-2-enoyl]carbamate | ethyl N-[2-(ethoxycarbonylcarbamoyl)-3-[(4-methylphenyl)amino]prop-2-enoyl]carbamate
Type:
Small organic molecule
Emp. Form.:
C17H21N3O6
Mol. Mass.:
363.3651
SMILES:
CCOC(=O)NC(=O)C(C=Nc1ccc(C)cc1)C(=O)NC(=O)OCC |w:10.10|
Structure:
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