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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM60074
Substrate
n/a
Meas. Tech.
Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2
IC50
>79400±0 nM
Citation
 PubChem, PC Dose Response confirmation of HTS hits from an HePTP Fluorescent Assay using OMFP substrate - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM60074
Synonyms:
2-[(3,4-difluoroanilino)-oxomethyl]-1-cyclohexanecarboxylic acid | 2-[(3,4-difluoroanilino)carbonyl]cyclohexanecarboxylic acid | 2-[(3,4-difluorophenyl)carbamoyl]cyclohexane-1-carboxylic acid | 2-[(3,4-difluorophenyl)carbamoyl]cyclohexanecarboxylic acid | 2-[[3,4-bis(fluoranyl)phenyl]carbamoyl]cyclohexane-1-carboxylic acid | MLS000700945 | SMR000231199 | cid_4054405
Type:
Small organic molecule
Emp. Form.:
C14H15F2NO3
Mol. Mass.:
283.2706
SMILES:
OC(=O)C1CCCCC1C(=O)Nc1ccc(F)c(F)c1
Structure:
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