Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM75339
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2
IC50
12900±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit VHR1, Fluorescent Assay - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM75339
Synonyms:
(3E)-3-[2-(3,4-dichlorophenyl)-1H-1,2,3,4-tetrazol-5-ylidene]-6-methoxy-quinolin-2-one | (3E)-3-[2-(3,4-dichlorophenyl)-1H-tetrazol-5-ylidene]-6-methoxy-2-quinolinone | (3E)-3-[2-(3,4-dichlorophenyl)-1H-tetrazol-5-ylidene]-6-methoxy-carbostyril | (3E)-3-[2-(3,4-dichlorophenyl)-1H-tetrazol-5-ylidene]-6-methoxyquinolin-2-one | MLS-0067105.0001 | cid_16654617
Type:
Small organic molecule
Emp. Form.:
C17H11Cl2N5O2
Mol. Mass.:
388.208
SMILES:
COc1ccc2nc(O)c(cc2c1)-c1nnn(n1)-c1ccc(Cl)c(Cl)c1
Structure:
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