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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM54792
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit HePTP - Set 2
IC50
32300±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM54792
Synonyms:
2-(3-cyano-5,8-dimethyl-quinolin-2-yl)sulfanyl-N-(2-ethyl-6-methyl-phenyl)ethanamide | 2-(3-cyano-5,8-dimethylquinolin-2-yl)sulfanyl-N-(2-ethyl-6-methylphenyl)acetamide | 2-[(3-cyano-5,8-dimethyl-2-quinolinyl)thio]-N-(2-ethyl-6-methylphenyl)acetamide | 2-[(3-cyano-5,8-dimethyl-2-quinolyl)thio]-N-(2-ethyl-6-methyl-phenyl)acetamide | CHEMBL1713374 | MLS-0412203.0001 | cid_1450182
Type:
Small organic molecule
Emp. Form.:
C23H23N3OS
Mol. Mass.:
389.513
SMILES:
CCc1cccc(C)c1NC(=O)CSc1nc2c(C)ccc(C)c2cc1C#N
Structure:
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