Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM65968
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit HePTP - Set 2
IC50
100000±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM65968
Synonyms:
2-[4-[(1Z)-1-(benzoylhydrazinylidene)ethyl]phenoxy]acetic acid | 2-[4-[(Z)-N-benzamido-C-methyl-carbonimidoyl]phenoxy]acetic acid | 2-[4-[(Z)-N-benzamido-C-methyl-carbonimidoyl]phenoxy]ethanoic acid | 2-[4-[(Z)-N-benzamido-C-methylcarbonimidoyl]phenoxy]acetic acid | MLS-0435439.0001 | cid_6013639
Type:
Small organic molecule
Emp. Form.:
C17H16N2O4
Mol. Mass.:
312.3199
SMILES:
CC(=NNC(=O)c1ccccc1)c1ccc(OCC(O)=O)cc1 |w:2.2|
Structure:
Search PDB for entries with ligand similarity: