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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM65970
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit HePTP - Set 2
IC50
100000±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM65970
Synonyms:
2-[4-[[[3-[(2-methoxyphenyl)sulfamoyl]benzoyl]hydrazinylidene]methyl]phenoxy]acetic acid | 2-[4-[[[3-[(2-methoxyphenyl)sulfamoyl]benzoyl]hydrazono]methyl]phenoxy]acetic acid | 2-[4-[[[3-[(2-methoxyphenyl)sulfamoyl]phenyl]carbonylhydrazinylidene]methyl]phenoxy]ethanoic acid | 2-[4-[[[[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-oxomethyl]hydrazinylidene]methyl]phenoxy]acetic acid | MLS-0256798.0001 | cid_2127695
Type:
Small organic molecule
Emp. Form.:
C23H21N3O7S
Mol. Mass.:
483.494
SMILES:
COc1ccccc1NS(=O)(=O)c1cccc(c1)C(=O)NN=Cc1ccc(OCC(O)=O)cc1
Structure:
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