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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM75368
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit HePTP - Set 2
IC50
7930±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM75368
Synonyms:
1-(2,3-dihydro-1H-inden-5-yl)-3-(4-sulfamoylphenyl)thiourea | 1-indan-5-yl-3-(4-sulfamoylphenyl)thiourea | MLS-0435634.0001 | cid_970693
Type:
Small organic molecule
Emp. Form.:
C16H17N3O2S2
Mol. Mass.:
347.455
SMILES:
NS(=O)(=O)c1ccc(NC(=S)Nc2ccc3CCCc3c2)cc1
Structure:
Search PDB for entries with ligand similarity: