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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM75371
Substrate
n/a
Meas. Tech.
SAR analysis of compounds that inhibit HePTP - Set 2
IC50
47600±n/a nM
Citation
 PubChem, PC SAR analysis of compounds that inhibit HePTP - Set 2 PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM75371
Synonyms:
1-(4-methylphenyl)-3-(4-sulfamoylphenyl)urea | 1-(p-tolyl)-3-(4-sulfamoylphenyl)urea | MLS-0243497.0001 | cid_2238788
Type:
Small organic molecule
Emp. Form.:
C14H15N3O3S
Mol. Mass.:
305.352
SMILES:
Cc1ccc(NC(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1
Structure:
Search PDB for entries with ligand similarity: