Reaction Details Report a problem with these data
Target
Aryl hydrocarbon receptor
Ligand
BDBM75486
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR)
EC50
1118±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the Aryl Hydrocarbon Receptor (AHR) PubChem Bioassay (2010)[AID] 
Target
Name:
Aryl hydrocarbon receptor
Synonyms:
AHR | AHR_HUMAN | BHLHE76 | Class E basic helix-loop-helix protein 76 | aryl hydrocarbon receptor precursor
Type:
PROTEIN
Mol. Mass.:
96143.77
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1503828
Residue:
848
Sequence:
MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQGKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRWTWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPFPAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAPFENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLYSIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQQQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFVPFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYPMGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQHTHVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFPDLTSSGFL
  
Inhibitor
Name:
BDBM75486
Synonyms:
6-[[(4-chlorobenzylidene)amino]-ethyl-amino]-3-methyl-uracil | 6-[[(4-chlorophenyl)methylideneamino]-ethyl-amino]-3-methyl-1H-pyrimidine-2,4-dione | 6-[[(4-chlorophenyl)methylideneamino]-ethylamino]-3-methyl-1H-pyrimidine-2,4-dione | 6-{N'-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-N-ethyl-hydrazino}-3-methyl-1H-pyrimidine-2,4-dione | MLS000591319 | SMR000218910 | cid_3784808
Type:
Small organic molecule
Emp. Form.:
C14H15ClN4O2
Mol. Mass.:
306.748
SMILES:
CCN(N=Cc1ccc(Cl)cc1)c1cc(=O)n(C)c(=O)[nH]1 |w:3.2|
Structure:
Search PDB for entries with ligand similarity: