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Target
Oxytocin receptor
Ligand
BDBM75709
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high throughput dose response assay for potentiators of Oxytocin Receptor (OXTR)
EC50
>29898±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay for potentiators of Oxytocin Receptor (OXTR) PubChem Bioassay (2010)[AID] 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Homo sapiens (Human)
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM75709
Synonyms:
4-[(1,3-diphenyl-4-pyrazolyl)methylideneamino]-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione | 4-[(1,3-diphenylpyrazol-4-yl)methyleneamino]-3-(4-pyridyl)-1H-1,2,4-triazole-5-thione | 4-[(1,3-diphenylpyrazol-4-yl)methylideneamino]-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione | 4-{[(1,3-diphenyl-1H-pyrazol-4-yl)methylene]amino}-5-(4-pyridinyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione | MLS000858724 | SMR000458803 | cid_2815100
Type:
Small organic molecule
Emp. Form.:
C23H17N7S
Mol. Mass.:
423.493
SMILES:
S=c1[nH]nc(-c2ccncc2)n1N=Cc1cn(nc1-c1ccccc1)-c1ccccc1 |w:12.13|
Structure:
Search PDB for entries with ligand similarity: