Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM75715
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high throughput dose response screening assay for agonists of the vasopressin 1 receptor (V1R)
EC50
6678±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response screening assay for agonists of the vasopressin 1 receptor (V1R) PubChem Bioassay (2010)[AID] 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM75715
Synonyms:
6-bromanyl-2-(3-chlorophenyl)-3-oxidanyl-quinazolin-4-one | 6-bromo-2-(3-chlorophenyl)-3-hydroxy-4(3H)-quinazolinone | 6-bromo-2-(3-chlorophenyl)-3-hydroxy-4-quinazolinone | 6-bromo-2-(3-chlorophenyl)-3-hydroxy-quinazolin-4-one | 6-bromo-2-(3-chlorophenyl)-3-hydroxyquinazolin-4-one | MLS001165292 | SMR000549804 | cid_1471100
Type:
Small organic molecule
Emp. Form.:
C14H8BrClN2O2
Mol. Mass.:
351.583
SMILES:
On1c(nc2ccc(Br)cc2c1=O)-c1cccc(Cl)c1
Structure:
Search PDB for entries with ligand similarity: