BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAngiotensin II receptor
LigandBDBM67308
Substrate/Competitorn/a
Meas. Tech.Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor
IC50 16913±1623 nM
Citation PubChem, PC Dose Response screen for antagonists of Angiotensin II Receptor Type 1 to assess selectivity of uHTS small molecule antagonists hits of the APJ receptor PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Angiotensin II receptor
Name:Angiotensin II receptor
Synonyms:AT1 | AT1AR | AT1BR | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:Protein
Mol. Mass.:41080.75
Organism:Homo sapiens (Human)
Description:P30556
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM67308
NameBDBM67308
Synonyms:4-[1-(4-methylphenyl)-2-nitro-ethyl]sulfanylaniline | 4-[1-(4-methylphenyl)-2-nitroethyl]sulfanylaniline | 4-[[1-(4-methylphenyl)-2-nitroethyl]thio]aniline | 4-{[1-(4-methylphenyl)-2-nitroethyl]thio}aniline | MLS000861888 | SMR000460672 | [4-[[2-nitro-1-(p-tolyl)ethyl]thio]phenyl]amine | cid_2733001
TypeSmall organic molecule
Emp. Form.C15H16N2O2S
Mol. Mass.288.365
SMILESCc1ccc(cc1)C(C[N+]([O-])=O)Sc1ccc(N)cc1
Structure
n/a