Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM75868
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 5
IC50
4600±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 5 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM75868
Synonyms:
1-(4-chlorophenyl)-5-[(E)-(thiocarbamoylhydrazono)methyl]pyrazole-4-carboxylic acid methyl ester | 5-[(E)-(carbamothioylhydrazinylidene)methyl]-1-(4-chlorophenyl)-4-pyrazolecarboxylic acid methyl ester | MLS-0297592.0001 | cid_9581014 | methyl 5-[(E)-(carbamothioylhydrazinylidene)methyl]-1-(4-chlorophenyl)pyrazole-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C13H12ClN5O2S
Mol. Mass.:
337.785
SMILES:
COC(=O)c1cnn(c1C=NNC(N)=S)-c1ccc(Cl)cc1 |w:10.11|
Structure:
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