Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM75871
Substrate
n/a
Meas. Tech.
SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 5
IC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Antagonists of the GPR35 Receptor using an Image-Based Assay - Set 5 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM75871
Synonyms:
1-[[(Z)-(3-phenylpyrazol-4-ylidene)methyl]amino]thiourea | MLS-0437448.0001 | [[(Z)-(3-phenyl-4-pyrazolylidene)methyl]amino]thiourea | [[(Z)-(3-phenylpyrazol-4-ylidene)methyl]amino]thiourea | cid_5335766
Type:
Small organic molecule
Emp. Form.:
C11H11N5S
Mol. Mass.:
245.304
SMILES:
NC(=S)NN=Cc1c[nH]nc1-c1ccccc1 |w:4.3|
Structure:
Search PDB for entries with ligand similarity: