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Target
G-protein coupled receptor 55
Ligand
BDBM61632
Substrate
n/a
Meas. Tech.
SAR Analysis of Selective Antagonists of GPR55 using an Image-Based Assay - Set 3
IC50
9080±n/a nM
Citation
 PubChem, PC SAR Analysis of Selective Antagonists of GPR55 using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 55
Synonyms:
G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN
Type:
PROTEIN
Mol. Mass.:
36649.72
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1292265
Residue:
319
Sequence:
MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
  
Inhibitor
Name:
BDBM61632
Synonyms:
5-[(E)-(tert-butylthiocarbamoylhydrazono)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylic acid methyl ester | 5-[(tert-butylthiocarbamoylhydrazono)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylic acid methyl ester | 5-[[[(tert-butylamino)-sulfanylidenemethyl]hydrazinylidene]methyl]-1-(2,4-difluorophenyl)-4-pyrazolecarboxylic acid methyl ester | MLS000834953 | SMR000461569 | cid_2745687 | methyl 1-[2,4-bis(fluoranyl)phenyl]-5-[(tert-butylcarbamothioylhydrazinylidene)methyl]pyrazole-4-carboxylate | methyl 5-[(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate | methyl 5-{2-[(tert-butylamino)carbothioyl]carbohydrazonoyl}-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C17H19F2N5O2S
Mol. Mass.:
395.427
SMILES:
COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F |w:10.11|
Structure:
Search PDB for entries with ligand similarity: