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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM75913
Substrate
n/a
Meas. Tech.
Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)
IC50
>20000±n/a nM
Citation
 PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM75913
Synonyms:
(E)-3-[5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)-4-pyridazinyl]-2-propenoic acid methyl ester | (E)-3-[6-keto-5-(4-methoxyphenoxy)-1-p-cumenyl-pyridazin-4-yl]acrylic acid methyl ester | SR-02000000442 | SR-02000000442-1 | cid_46835814 | methyl (E)-3-[5-(4-methoxyphenoxy)-6-oxidanylidene-1-(4-propan-2-ylphenyl)pyridazin-4-yl]prop-2-enoate | methyl (E)-3-[5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)pyridazin-4-yl]prop-2-enoate
Type:
Small organic molecule
Emp. Form.:
C24H24N2O5
Mol. Mass.:
420.4578
SMILES:
COC(=O)\C=C\c1cnn(-c2ccc(cc2)C(C)C)c(=O)c1Oc1ccc(OC)cc1
Structure:
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