Reaction Details Report a problem with these data
Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM75956
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists
IC50
8458±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM75956
Synonyms:
3-Methyl-benzofuran-2-carboxylic acid (4-tetrazol-1-yl-phenyl)-amide | 3-methyl-N-[4-(1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | 3-methyl-N-[4-(1-tetrazolyl)phenyl]-2-benzofurancarboxamide | 3-methyl-N-[4-(tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | 3-methyl-N-[4-(tetrazol-1-yl)phenyl]coumarilamide | MLS000068640 | SMR000003826 | cid_648856
Type:
Small organic molecule
Emp. Form.:
C17H13N5O2
Mol. Mass.:
319.3174
SMILES:
Cc1c(oc2ccccc12)C(=O)Nc1ccc(cc1)-n1cnnn1
Structure:
Search PDB for entries with ligand similarity: