Reaction Details Report a problem with these data
Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM41013
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists
IC50
861.97±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM41013
Synonyms:
4-methoxy-N-(7-methyl-2-thiazolo[4,5-g][1,3]benzothiazolyl)benzamide | 4-methoxy-N-(7-methyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide | 4-methoxy-N-(7-methylthiazolo[4,5-g][1,3]benzothiazol-2-yl)benzamide | MLS000529759 | SMR000126767 | cid_4582891
Type:
Small organic molecule
Emp. Form.:
C17H13N3O2S2
Mol. Mass.:
355.434
SMILES:
COc1ccc(cc1)C(=O)Nc1nc2ccc3nc(C)sc3c2s1
Structure:
Search PDB for entries with ligand similarity: