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Target
Photoreceptor-specific nuclear receptor
Ligand
BDBM76018
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists
IC50
6553±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay (2010)[AID] 
Target
Name:
Photoreceptor-specific nuclear receptor
Synonyms:
NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor
Type:
PROTEIN
Mol. Mass.:
44699.83
Organism:
Homo sapiens (Human)
Description:
ChEMBL_401901
Residue:
410
Sequence:
METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYGIYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
  
Inhibitor
Name:
BDBM76018
Synonyms:
MLS001120732 | N-[3-(1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | N-[3-(1-tetrazolyl)phenyl]-2-benzofurancarboxamide | N-[3-(tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | N-[3-(tetrazol-1-yl)phenyl]coumarilamide | SMR000671653 | cid_7709970
Type:
Small organic molecule
Emp. Form.:
C16H11N5O2
Mol. Mass.:
305.2908
SMILES:
O=C(Nc1cccc(c1)-n1cnnn1)c1cc2ccccc2o1
Structure:
Search PDB for entries with ligand similarity: