Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM76049
Substrate
n/a
Meas. Tech.
SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of agonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM76049
Synonyms:
1-cyclopentyl-2-imino-5-keto-N-phenethyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 1-cyclopentyl-2-imino-5-oxo-N-(2-phenylethyl)-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide | 1-cyclopentyl-2-imino-5-oxo-N-(2-phenylethyl)dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 2-azanylidene-1-cyclopentyl-5-oxidanylidene-N-(2-phenylethyl)dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | MLS-0437146.0001 | cid_1077547
Type:
Small organic molecule
Emp. Form.:
C25H25N5O2
Mol. Mass.:
427.4983
SMILES:
N=c1c(cc2c(nc3ccccn3c2=O)n1C1CCCC1)C(=O)NCCc1ccccc1
Structure:
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