Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM76082
Substrate
n/a
Meas. Tech.
SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4
IC50
850±n/a nM
Citation
 PubChem, PC SAR analysis of antagonists of the Cannabinoid Receptor 1 using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM76082
Synonyms:
(6Z)-3-ethoxy-6-[4-(4-methoxyphenyl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone | (6Z)-3-ethoxy-6-[4-(4-methoxyphenyl)-5-methyl-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one | (6Z)-3-ethoxy-6-[4-(4-methoxyphenyl)-5-methyl-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one | MLS-0437221.0001 | cid_5423853
Type:
Small organic molecule
Emp. Form.:
C19H20N2O3
Mol. Mass.:
324.3737
SMILES:
CCOc1ccc(-c2n[nH]c(C)c2-c2ccc(OC)cc2)c(O)c1
Structure:
Search PDB for entries with ligand similarity: