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Target
G-protein coupled receptor 35
Ligand
BDBM76043
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM76043
Synonyms:
1-cyclopentyl-2-imino-5-keto-N-methyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 1-cyclopentyl-2-imino-N-methyl-5-oxo-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxamide | 1-cyclopentyl-2-imino-N-methyl-5-oxodipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | 2-azanylidene-1-cyclopentyl-N-methyl-5-oxidanylidene-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxamide | MLS-0437141.0001 | cid_706463
Type:
Small organic molecule
Emp. Form.:
C18H19N5O2
Mol. Mass.:
337.3758
SMILES:
CNC(=O)c1cc2c(nc3ccccn3c2=O)n(C2CCCC2)c1=N
Structure:
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