Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM76078
Substrate
n/a
Meas. Tech.
SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR analysis of Agonists of the GPR35 Receptor using an Image-Based Assay - Set 4 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM76078
Synonyms:
MLS-0205133.0001 | N-[4-(diethylsulfamoyl)phenyl]-2-phenyl-4-quinolinecarboxamide | N-[4-(diethylsulfamoyl)phenyl]-2-phenyl-cinchoninamide | N-[4-(diethylsulfamoyl)phenyl]-2-phenyl-quinoline-4-carboxamide | N-[4-(diethylsulfamoyl)phenyl]-2-phenylquinoline-4-carboxamide | cid_1306259
Type:
Small organic molecule
Emp. Form.:
C26H25N3O3S
Mol. Mass.:
459.56
SMILES:
CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)-c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: