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Target
General amino acid permease AGP1
Ligand
BDBM58019
Substrate
n/a
Meas. Tech.
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically AGP1
EC50
774800±n/a nM
Citation
 PubChem, PC Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically AGP1 PubChem Bioassay (2011)[AID] 
Target
Name:
General amino acid permease AGP1
Synonyms:
AGP1 | AGP1_YEAST | Agp1p
Type:
Enzyme Catalytic Domain
Mol. Mass.:
69674.09
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_85666113
Residue:
633
Sequence:
MSSSKSLYELKDLKNSSTEIHATGQDNEIEYFETGSNDRPSSQPHLGYEQHNTSAVRRFFDSFKRADQGPQDEVEATQMNDLTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEMALVYSNLTGGYNAYPSFLVDDGFGFAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIILLGFLVPYNSDQLLGSTGGGTKASPYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYSSARLFLTLSEQGYAPKVFSYIDRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQLFTWTAICLSHLRFRRAMKVQGRSLGELGFKSQTGVWGSAYACIMMILILIAQFWVAIAPIGEGKLDAQAFFENYLAMPILIALYVGYKVWHKDWKLFIRADKIDLDSHRQIFDEELIKQEDEEYRERLRNGPYWKRVVAFWC
  
Inhibitor
Name:
BDBM58019
Synonyms:
5-methyl-N-(4-pyridin-2-yl-1,3-thiazol-2-yl)furan-2-carboxamide | 5-methyl-N-[4-(2-pyridinyl)-2-thiazolyl]-2-furancarboxamide | 5-methyl-N-[4-(2-pyridyl)thiazol-2-yl]-2-furamide | MLS001010722 | SMR000385065 | cid_2466262
Type:
Small organic molecule
Emp. Form.:
C14H11N3O2S
Mol. Mass.:
285.321
SMILES:
Cc1ccc(o1)C(=O)Nc1nc(cs1)-c1ccccn1
Structure:
Search PDB for entries with ligand similarity: