Reaction Details Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM34183
Substrate
n/a
Meas. Tech.
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19A
EC50
55730±n/a nM
Citation
 PubChem, PC Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically RPL19A PubChem Bioassay (2011)[AID] 
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM34183
Synonyms:
2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylacetic acid ethyl ester | 2-[[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]acetic acid ethyl ester | MLS000049112 | SMR000074423 | cid_1151859 | ethyl 2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylacetate | ethyl 2-[4-phenyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylethanoate | ethyl {[4-phenyl-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl}acetate
Type:
Small organic molecule
Emp. Form.:
C15H13F3N2O4S
Mol. Mass.:
374.335
SMILES:
CCOC(=O)CS(=O)(=O)c1nc(cc(n1)C(F)(F)F)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: