Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM75373
Substrate
n/a
Meas. Tech.
SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay - Set 3
EC50
>32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Agonists of the MOR Receptor using an Image-Based Assay - Set 3 PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM75373
Synonyms:
2-[4-(2-furanylmethyl)-5-[(4-nitrophenyl)methylthio]-1,2,4-triazol-3-yl]pyridine | 2-[4-(2-furfuryl)-5-[(4-nitrobenzyl)thio]-1,2,4-triazol-3-yl]pyridine | 2-[4-(furan-2-ylmethyl)-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine | KSC-5-287A1 | KUC104176N | cid_1423675
Type:
Small organic molecule
Emp. Form.:
C19H15N5O3S
Mol. Mass.:
393.419
SMILES:
[O-][N+](=O)c1ccc(CSc2nnc(-c3ccccn3)n2Cc2ccco2)cc1
Structure:
Search PDB for entries with ligand similarity: