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Target
Vacuolar aminopeptidase 1
Ligand
BDBM76303
Substrate
n/a
Meas. Tech.
Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically LAP4
EC50
86410±n/a nM
Citation
 PubChem, PC Confirmatory Cherry Pick 3 SAR Dose Response Multiplex in TOR pathway GFP-fusion proteins for Saccharomyes cerevisiae, specifically LAP4 PubChem Bioassay (2011)[AID] 
Target
Name:
Vacuolar aminopeptidase 1
Synonyms:
AMPL_YEAST | APE1 | API | LAP4 | YSC1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57084.90
Organism:
Saccharomyces cerevisiae
Description:
gi_486173
Residue:
514
Sequence:
MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
  
Inhibitor
Name:
BDBM76303
Synonyms:
4-chloranyl-3-(2-chloroethyl)-8-methoxy-2-methyl-quinoline | 4-chloro-3-(2-chloroethyl)-2-methyl-8-quinolinyl methyl ether | 4-chloro-3-(2-chloroethyl)-8-methoxy-2-methyl-quinoline | 4-chloro-3-(2-chloroethyl)-8-methoxy-2-methylquinoline | MLS000720591 | SMR000336339 | cid_3332664
Type:
Small organic molecule
Emp. Form.:
C13H13Cl2NO
Mol. Mass.:
270.154
SMILES:
COc1cccc2c(Cl)c(CCCl)c(C)nc12
Structure:
Search PDB for entries with ligand similarity: