Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM76337
Substrate
n/a
Meas. Tech.
Dose Response Confirmation of compounds that inhibit VHR1 in Fluorescent Assay
IC50
7200±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of compounds that inhibit VHR1 in Fluorescent Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM76337
Synonyms:
10-methyl-3-(2-pyridin-2-ylethynyl)acridin-9-one | 10-methyl-3-[2-(2-pyridinyl)ethynyl]-9-acridinone | 10-methyl-3-[2-(2-pyridyl)ethynyl]acridin-9-one | MLS001250121 | SMR000685987 | cid_24792649
Type:
Small organic molecule
Emp. Form.:
C21H14N2O
Mol. Mass.:
310.3487
SMILES:
Cn1c2ccccc2c(=O)c2ccc(cc12)C#Cc1ccccn1
Structure:
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