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Target
Sentrin-specific protease 8
Ligand
BDBM42197
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2040±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM42197
Synonyms:
10-(4-chlorophenyl)-[1,3]thiazolo[3,2-a]perimidine | 10-(4-chlorophenyl)[1,3]thiazolo[3,2-a]perimidine | 10-(4-chlorophenyl)thiazolo[3,2-a]perimidine | MLS000594502 | SMR000115638 | cid_1818715
Type:
Small organic molecule
Emp. Form.:
C19H11ClN2S
Mol. Mass.:
334.822
SMILES:
Clc1ccc(cc1)-c1csc2nc3cccc4cccc(c34)n12
Structure:
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