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Target
Sentrin-specific protease 8
Ligand
BDBM57516
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50
2050±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM57516
Synonyms:
4-[2-[[4-(2-chlorobenzoyl)oxyphenyl]methylidene]hydrazinyl]benzoic acid | 4-[2-[[4-(2-chlorophenyl)carbonyloxyphenyl]methylidene]hydrazinyl]benzoic acid | 4-[2-[[4-[(2-chlorophenyl)-oxomethoxy]phenyl]methylidene]hydrazinyl]benzoic acid | 4-[N'-[4-(2-chlorobenzoyl)oxybenzylidene]hydrazino]benzoic acid | MLS000589715 | SMR000219532 | cid_3969890
Type:
Small organic molecule
Emp. Form.:
C21H15ClN2O4
Mol. Mass.:
394.808
SMILES:
OC(=O)c1ccc(cc1)N=NCc1ccc(OC(=O)c2ccccc2Cl)cc1 |w:9.9|
Structure:
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