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Target
Sentrin-specific protease 8
Ligand
BDBM34581
Substrate
n/a
Meas. Tech.
Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Luminescent Interference Counterscreen assay
IC50
>5000±0 nM
Citation
 PubChem, PC Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Luminescent Interference Counterscreen assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM34581
Synonyms:
2-amino-1-(3-methoxypropyl)-N-sec-butyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-butan-2-yl-1-(3-methoxypropyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-amino-N-butan-2-yl-1-(3-methoxypropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-azanyl-N-butan-2-yl-1-(3-methoxypropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000040978 | SMR000043134 | cid_662388
Type:
Small organic molecule
Emp. Form.:
C19H25N5O2
Mol. Mass.:
355.4341
SMILES:
CCC(C)NC(=O)c1c(N)n(CCCOC)c2nc3ccccc3nc12
Structure:
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