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Target
Sentrin-specific protease 8
Ligand
BDBM33185
Substrate
n/a
Meas. Tech.
Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Luminescent Interference Counterscreen assay
IC50
>5000±0 nM
Citation
 PubChem, PC Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Luminescent Interference Counterscreen assay PubChem Bioassay (2010)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM33185
Synonyms:
4-({(4Z)-1-oxo-4-[(phenylsulfonyl)imino]-1,4-dihydronaphthalen-2-yl}amino)benzoic acid | 4-[(4-besylimino-1-keto-2-naphthyl)amino]benzoic acid | 4-[[(4Z)-4-besylimino-1-keto-2-naphthyl]amino]benzoic acid | 4-[[1-oxidanylidene-4-(phenylsulfonylimino)naphthalen-2-yl]amino]benzoic acid | 4-[[4-(benzenesulfonylimino)-1-oxo-2-naphthalenyl]amino]benzoic acid | 4-[[4-(benzenesulfonylimino)-1-oxonaphthalen-2-yl]amino]benzoic acid | MLS000686314 | SMR000313157 | cid_4053104
Type:
Small organic molecule
Emp. Form.:
C23H16N2O5S
Mol. Mass.:
432.449
SMILES:
OC(=O)c1ccc(NC2=CC(=NS(=O)(=O)c3ccccc3)c3ccccc3C2=O)cc1 |w:11.11,t:8|
Structure:
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