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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM76332
Substrate
n/a
Meas. Tech.
Dose Response confirmation of compounds that inhibit HePTP
IC50
4690±n/a nM
Citation
 PubChem, PC Dose Response confirmation of compounds that inhibit HePTP PubChem Bioassay (2010)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM76332
Synonyms:
MLS000325167 | N-[5-(1,3-benzothiazol-2-yl)-2-methyl-phenyl]-2-chloranyl-5-(1,2,4-triazol-4-yl)benzamide | N-[5-(1,3-benzothiazol-2-yl)-2-methyl-phenyl]-2-chloro-5-(1,2,4-triazol-4-yl)benzamide | N-[5-(1,3-benzothiazol-2-yl)-2-methylphenyl]-2-chloro-5-(1,2,4-triazol-4-yl)benzamide | N-[5-(1,3-benzothiazol-2-yl)-2-methylphenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide | SMR000160747 | cid_1017700
Type:
Small organic molecule
Emp. Form.:
C23H16ClN5OS
Mol. Mass.:
445.924
SMILES:
Cc1ccc(cc1NC(=O)c1cc(ccc1Cl)-n1cnnc1)-c1nc2ccccc2s1
Structure:
Search PDB for entries with ligand similarity: